KAN0438757 是一种有效的选择性代谢激酶 PFKFB3 抑制剂，IC50 值为 0.19 μM。
CAS：1451255-59-6
分子式：C21H18FNO7S
分子量：447.43
纯度：98%
存储：Store at -20°C

Background:

KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM [1]. IC50: 0.19 μM (PFKFB3)[1]

[1]. Gustafsson NMS, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018 Sep 24;9(1):3872.