Panepoxydone is a fungal metabolite that inhibits NF-κB transcription factor by preventing IκB phosphorylation, thus inhibiting the release of NF-κB from NF-κB complex and its translocation into the nucleus. Panepoxydone also has antimalarial, cytotoxic activities and anti-parasitic activity against Trypanosoma cruzi. References: Vásquez R, Rios N, Solano G, Cubilla-Rios L. Lentinoids A-D, New Natural Products Isolated from Lentinus strigellus. Molecules. 2018 Mar 28;23(4). pii: E773. doi: 10.3390/molecules23040773. PubMed PMID: 29597242; PubMed Central PMCID: PMC6017980.
纯度:≥98%
CAS:31298-54-1