MutantIDH1-IN-4(compound434)是一种突变型异柠檬酸脱氢酶1(IDH1)的抑制剂，其对R132H、HT1080和U87R132H细胞中的突变型IDH1的IC50值≤0.5μM。
CAS：1416270-18-2
分子式：C25H34N4O3
分子量：438.56
纯度：98%
存储：Store at -20°C

Background:

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ≤ 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells[1].

[1]. US20170210749A1.