ML-226 is an inhibitor of α/β hydrolase domain-containing protein 11 (ABHD11) that inhibits ABHD11 in vitro and in situ (IC50s = 15 and 0.68 nM, respectively).
CAS：2055172-43-3
分子式：C23H26N4O2
分子量：390.5
纯度：98%
存储：Store at -20°C

Background:

ML-226 is an inhibitor of α/β hydrolase domain-containing protein 11 (ABHD11) that inhibits ABHD11 in vitro and in situ (IC50s = 15 and 0.68 nM, respectively). It is 100-fold selective for ABHD11 over approximately 20 other serine hydrolases. ML-226 covalently carbamoylates the active site serine of ABHD11. It can be used as an anti-probe for ML-211 , an inhibitor of the protein palmitoyl thioesterases lysophospholipase 1 (LYPLA1) and LYPA2.