BAY-293是一种有效的SOS1抑制剂，通过破坏RAS-SOS1相互作用阻断RAS活化，IC50为21nM。
CAS：2244904-70-7
分子式：C25H28N4O2S
分子量：448.58
纯度：98%
存储：Store at -20°C
Background:
BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM[1].
[1]. Hillig RC, et al. Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1interaction. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2551-2560.
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