Pareptidemonohydrochloride是一种促黑素抑制因子(MIF)的类似物。
CAS：63236-23-7
分子式：C14H27ClN4O3
分子量：334.84
纯度：98%
存储：Store at -20°C

Background:

Pareptide monohydrochloride is a melanotropin-inhibiting factor (MIF) metabolically stable analogue.

Chronic coadministration of Pareptide (0.25 mg/kg, SC, BID, 3.5 days) to mice pretreated with Haloperidol (8.0 mg/kg, IP, BID, 3 days) significantly increases the cataleptic effects of a smaller challenge dose of Haloperidol (2.0 mg/kg, IP) given 15 hours after the last pretreatment injections (p<0.01)[1].

[1]. Mycroft FJ, et al. Pro-Leu-Gly-NH2 and Pareptide inhibit development of tolerance to Haloperidol catalepsy in the mouse. Peptides. 1984 Sep-Oct;5(5):883-7.