Dihydrorhodamine123是一种荧光探针(λex=488nm，λem=525nm)。
CAS：109244-58-8
分子式：C21H18N2O3
分子量：346.38
纯度：98%
存储：Store at -20°C

Background:

Dihydrorhodamine 123 is a fluorescent probe (λex=488 nm, λem=525 nm).

In the presence of 10 μM Dihydrorhodamine 123 (DHR) the stimulation of the neutrophil NADPH oxidase by the addition of 50 nM phorbol 12-myristate 13-acetat (PMA) resultes in an increase in the rate of rhodamine generation. The fluorescent intensity of the cells, in the presence of 10 μM Dihydrorhodamine 123, increases with time following the addition of 50 nM PMA. In the presence of 10 μM Dihydrorhodamine 123, induced HL60 cells show a sustained increase in fluorescence following the addition of 50 nM PMA[1].

[1]. Lydia M. Henderson et al. Dihydrorhodamine 123: a fluorescent probe for superoxide generation? Eur.J.Biochem. 217, 973-980.