CADD522 是一种有效的 runt 相关转录因子-2 (RUNX2)-DNA 结合的抑制剂，IC50 为 10 nM。CADD522 具有抗肿瘤活性。
CAS：199735-88-1
分子式：C15H13Cl2NO3
分子量：326.17
纯度：98%
存储：Store at -20°C

Background:

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity[1]. RUNX2-DNA binding[1]

[1]. Kim MS, et al. Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity. Oncotarget. 2017 Aug 10;8(41):70916-70940.