您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > Taprenepag isopropyl(PF-04217329)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Taprenepag isopropyl(PF-04217329)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Taprenepag isopropyl(PF-04217329)图片
CAS NO:1005549-94-9
规格:98%
分子量:520.6
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Taprenepagisopropyl是一个具有高度选择性的EP2受体激动剂。
CAS:1005549-94-9
分子式:C27H28N4O5S
分子量:520.6
纯度:98%
存储:Store at -20°C

Background:

Taprenepag isopropyl is a highly selective EP2 receptor agonist.



Taprenepag isopropyl is a highly selective EP2 receptor agonist. Intraocular pressure (IOP) in the left, vehicle-dosed eye typically remains within the normal range. In the right (Taprenepag isopropyl-dosed) eye, IOP is reduced in all dose groups. In the high-dose group, IOP is reduced to the extent that it cannot be measured (<4mm Hg) on Days 22 and 29. There are no clinical signs or changes in body weight observed with any dose of Taprenepag isopropyl administration, and noocular findings occur for animals in the low-dose group (0.75 mg/day)[1].


[1]. Yanochko GM, et al. Investigation of ocular events associated with taprenepag isopropyl, a topical EP2 agonist in development for treatment of glaucoma. J Ocul Pharmacol Ther. 2014 Jun;30(5):429-39.