Enoximone is a novel and selective phosphodiesterase III (PDE3) inhibitor with an IC50 of 5.9 μM and with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. Enoximone prevents the degradation of cAMP by PDE, which prolongs signal transduction and its subsequent effects. It is used in patients with congestive heart failure.
纯度:≥98%
CAS:77671-31-9