Asoprisnil (J867) 是一种选择性孕激素受体 (progesterone receptor) 调节剂，对动物和人类中各种孕酮靶向组织具有混合的孕酮激动剂和拮抗剂作用。
CAS：199396-76-4
分子式：C28H35NO4
分子量：449.58
纯度：98%
存储：Store at -20°C

Background:

Asoprisnil (J867), a selective progesterone receptor modulator, exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human[1].

[1]. Stewart EA, et al. Safety and efficacy of the selective progesterone receptor modulator asoprisnil for heavy menstrual bleeding with uterine fibroids: pooled analysis of two 12-month, placebo-controlled, randomized trials. Hum Reprod. 2019 Apr 1;34(4):623-634. [2]. Wu XL, et al. Postcoital administration of asoprisnil inhibited embryo implantation and disturbed ultrastructure of endometrium in implantation window in mice. J Huazhong Univ Sci Technolog Med Sci. 2013 Apr;33(2):277-283.