Fabomotizole盐酸盐(CM346盐酸盐)是一种具有抗焦虑和神经保护活性的化合物。
CAS：173352-39-1
分子式：C15H22ClN3O2S
分子量：343.87
纯度：98%
存储：Store at -20°C

Background:

Fabomotizole Hcl (CM346 Hcl) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.IC50 value:Target: anxiolytic agent Afobazole’s mechanism of action remains poorly defined however, with GABAergic, NGF and BDNF release promoting, MT1 receptor antagonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Afobazole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Afobazole has found little clinical use outside of Russia and has not been evaluated by the FDA.

[1]. Afobazole, From Wikipedia