I-SAP is a high affinity TP receptor antagonist.
CAS：133538-58-6
分子式：C22H30INO4S
分子量：531.4
纯度：98%
存储：Store at -20°C

Background:

I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and 490 pM at pH 6.5.