neurotoxin that destroys dopaminergic and noradrenergic (catecholaminergic) neurons
CAS：636-00-0
分子式：C8H11NO3.HBr
分子量：250.09
纯度：98%
存储：Store at -20°C

Background:

Oxidopamine hydrobromide (6-OHDA hydrobromide), an?antagonist?of the neurotransmitter dopamine, is a widely used neurotoxin that selectively destroys dopaminergic neurons.

参考文献:
[1]. Fujita H et al. Cell-permeable cAMP analog suppresses 6-hydroxydopamine-induced apoptosis in PC12 cells through the activation of the Akt pathway. Brain Res. 2006 Oct 3;1113(1):10-23.
[2]. Soto-Otero R et al. Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease. J Neurochem. 2000 Apr;74(4):1605-12.