BQ788 is a novel, potent and selective ETB (endothelin B) receptor antagonist, attenuating stab wound injury-induced reactive astrocytes in rat brain and inhibiting ET-1 binding to ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells. BQ788 were well tolerated and showed signs of directly and indirectly reducing the viability of melanoma cells.

纯度：≥98%

CAS：156161-89-6