NAB 2 is an inhibitor of α-synuclein-induced toxicity.
CAS：1504588-00-4
分子式：C23H20ClN3O
分子量：389.9
纯度：98%
存储：Store at -20°C

Background:

NAB 2 is an inhibitor of α-synuclein-induced toxicity. It prevents α-synuclein-induced defects in Rsp5-dependent endocytosis and vacuolar delivery of Mup1, Golgi-to-vacuole trafficking of Sna3, and degradation of Bap2 in wild-type yeast cells. NAB 2 also prevents formation of α-synuclein foci in wild-type yeast cells, an effect that is prevented by the rsp5G747E point mutation.