PX20606transracemate是一种FXR激动剂，在FRET和M1H测定中对于FXR的EC50值分别为32和34nM。
CAS：1268244-85-4
分子式：C29H22Cl3NO4
分子量：554.85
纯度：98%
存储：Store at -20°C
Background:
PX20606 trans racemate is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively.
[1]. Kinzel O, et al. Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3746-53.
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