Maleimide-PEG4-NHS, formerly known as Mal-PEG4-NHS, is a sulfhydryl and amine reactive heterofuncational PEG linker. The chemical bonds formed through Maleimide-PEG4-NHS linker are stable and are not cleavable. The NHS ester reacts with amino groups at pH 7-9 to form stable amide bond while maleimide reacts with thiol groups at pH 6.5-7.5 to form stable thiol-ether bond. Maleimide-PEG4-NHS is a useful linker for various biomolecule crosslinking applications (such as to make antibody drug conjugates (ADCs). References:
纯度:≥98%
CAS:1286754-10-6