17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor
CAS:330203-01-5
分子式:C17H12BrNO3S2
分子量:422.32
纯度:98%
存储:Store at -20°C
Background:
TC HSD 21 is a potent 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) inhibitor with an IC50 of 14 nM. TC HSD 21 shows excellent selectivity over 17β-HSD isoenzymes and nuclear receptors[1].
参考文献:
[1]. Harada K,et al. Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):504-7.