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Pitavastatin Calcium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pitavastatin Calcium图片
CAS NO:147526-32-7
规格:98%
分子量:880.98
包装与价格:
包装价格(元)
10mg电议
25mg电议

产品介绍
Enzyme HMGCR inhibitor
CAS:147526-32-7
分子式:C50H46CaF2N2O8
分子量:880.98
纯度:98%
存储:Store at -20°C

Background:

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.