EEDinhibitor-1是EED的抑制剂,来自专利US20160176882A1,化合物实例2;在EEDAlphascreen,LC-MS和ELISA试验中的IC50s值分别为59,89,26nM。
CAS:1951408-58-4
分子式:C20H17FN6O
分子量:376.39
纯度:98%
存储:Store at -20°C
Background:
EED inhibitor-1 is an EED inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.
EED inhibitor-1 has antiproliferative activities in B cell lymphoma cell KARPAS422 after 14 days of treatment with an IC50 of 30 nM[1].
[1]. US20160176882 A1