Voxelotor(GBT440)是口服可用的镰状细胞血红蛋白调节剂。
CAS:1446321-46-5
分子式:C19H19N3O3
分子量:337.37
纯度:98%
存储:Store at -20°C
Background:
Voxelotor (GBT 440) is an orally bioavailable modulator of sickle cell hemoglobin.
[1]. Metcalf B, et al. Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. ACS Med Chem Lett. 2017 Jan 23;8(3):321-326.