L-858,051 is a water-soluble analog of forskolin, a cell-permeant activator of adenylate cyclase.
CAS:115116-37-5
分子式:C29H50N2O8.2HCl
分子量:609.6
纯度:98%
存储:Store at -20°C
Background:
L-858,051 is a water-soluble analog of forskolin , a cell-permeant activator of adenylate cyclase. L-858,051 activates adenylate cyclase (EC50 = 3 µM), inhibits glucose transport, and blocks cytochalasin B binding in rat adipocyte membranes. L-858,051 is used to activate adenylate cyclase and initiate signaling through elevated cAMP synthesis in a variety of cell types in culture.