positive allosteric modulator of AMPA receptors
CAS：1219633-99-4
分子式：C19H22N2O3S2
分子量：390.52
纯度：98%
存储：Store at -20°C

Background:

PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells.

参考文献:
[1]. Roberts BM, et al. Prevention of ketamine-induced working memory impairments by AMPA potentiators in a nonhuman primate model of cognitive dysfunction. Behav Brain Res. 2010 Sep 1;212(1):41-8.