Azumolene is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum.
CAS:105336-14-9
分子式:C13H8BrN4O3.Na
分子量:371.1
纯度:98%
存储:Store at -20°C
Background:
Azumolene is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum. It inhibits a component of store-operated calcium entry (SOCE) that is coupled to the skeletal muscle ryanodine receptor, with 20 µM azumolene causing a 70% reduction in SOCE in myotubes. Azumolene has utility in countering muscle dysfunction associated with malignant hyperthermia.