Fmoc-3VVD-OH是一种可降解(non-cleavable)的ADC连接桥，用于抗体药物结合物(ADCs)的合成。
货号:ajcx30664
CAS:863971-44-2
分子式:C36H51N3O7
分子量：637.81
溶解度:DMSO: ≥ 37 mg/mL (58.01 mM); H2O:< 0.1 mg/mL (insoluble)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Fmoc-3VVD-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Michinori Akaiwa, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018 May 31;3(5):5212-5221.