GNE-6468是一个有效且有选择性的RORγ(RORc)拮抗剂，对HEK-293细胞的EC50值为13nM。
货号:ajcx13104
CAS:1677668-27-7
分子式:C23H16ClN3O4
分子量：433.84
溶解度:DMSO: 5 mg/mL (11.52 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

GNE-6468 is a potent and selective RORγ(RORc) agonists with an EC50 value of 13 nM for HEK-293 cell.

[1]. Fauber BP, et al. Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists. Bioorg Med Chem Lett. 2015 Aug 1;25(15):2907-12.