Background:

Normeperidine-d₄(hydrochloride) (CRM) is a certified reference material intended for use as an internal standard for the quantification of normeperidine by GC- or LC-MS. Normeperidine is structurally categorized as an opioid. It is both a metabolite of and a precursor to meperidine , an opioid analgesic that is commonly abused.^1,2Normeperidine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

1.Ossipov, M.H., Harris, S., Lloyd, P., et al.Antinociceptive interaction between opioids and medetomidine: Systemic additivity and spinal synergyAnesthesiology73(6)1227-1235(1990) 2.Atluri, S.A., Sudarshan, G., and Manchikanti, L.Assessment of the trends in medical use and misuse of opioid analgesics from 2004 to 2011Pain Physician17(2)E119-E128(2014)