Thalidomide-O-C8-Boc是一种基于Thalidomide的,可募集CRBN蛋白的Cereblon配体。Thalidomide-O-C8-Boc可通过linker与靶蛋白配体连接,形成PROTAC分子。
货号:ajcx29730
CAS:2225148-52-5
分子式:C26H34N2O7
分子量:486.56
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Thalidomide-O-C8-Boc is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-C8-Boc can be connected to the ligand for protein by a linker to form PROTACs[1].
[1]. Nathanael S. Gray, et al. Degraders of wee1 kinase. WO2020069105A1.