(R,S)-Ivosidenib((R,S)-AG-120)是Ivosidenib(AG-120)的对映体,活性较低。
货号:ajcx29824
CAS:2070009-31-1
分子式:C28H22ClF3N6O3
分子量:582.96
溶解度:DMSO: 3.33 mg/mL (5.71 mM); H2O:< 0.1 mg/mL (insoluble)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
(R,S)-Ivosidenib ((R,S)-AG-120) is the less active enantiomer of Ivosidenib (AG-120)[1].
[1]. Popovici-Muller J, et al. Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1Mutant Cancers. ACS Med Chem Lett. 2018 Jan 19;9(4):300-305.