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NFAT inhibitor,Cell Permeable
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NFAT inhibitor,Cell Permeable图片
包装:1mg
规格:98%
市场价:2583元
分子量:3573.15

产品介绍
Cell permeable NFAT inhibitor
货号:ajcx27196
CAS:592517-80-1
分子式:C147H259N67O36S
分子量:3573.15
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs). Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. Cell permeable.


Elloumi et al (2012) A cell permeable peptide inhibitor of NFAT inhibits macrophage cytokine expression and ameliorates experimental colitis. PLoS One 7 e34172 PMID:22479554 |Noguchi et al (2004) A new cell-permeable peptide allows successful allogeneic islet transplantation in mice. Nat.Med. 10 305 PMID:14770176