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ASLAN003
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ASLAN003图片
规格:98%
分子量:356.32
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品介绍
ASLAN003 是一种具有口服活性,有效的 DHODH (人二氢乳清酸脱氢酶) 抑制剂,DHODH 是 AML (急性骨髓性白血病) 的新靶标。ASLAN003 具有抗肿瘤活性。
货号:ajcx14818
CAS:1035688-66-4
分子式:C19H14F2N2O3
分子量:356.32
溶解度:DMSO: 130 mg/mL (364.84 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

ASLAN003 is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) which has the potential to be a first-in-class candidate in AML (Acute Myelogenous Leukemia). ASLAN003 has antitumor activity[1].


[1]. Marco L. Lolli, et al. Human Dihydroorotate Dehydrogenase (hDHODH) as a new target on Acute Myelogenous Leukemia (AML): Targeting Myeloid Differentiation using Potent and Innovative hDHODH Inhibitors. 23rd Swedish Conference on Macromolecular Structure and Function TÄllberg, 14-17 June 2019