SORT-PGRNinteractioninhibitor1是一种有效的sortilin-progranulin相互作用的抑制剂，IC50为2μM。
货号:ajcx32360
CAS:100957-85-5
分子式:C15H18N2O2
分子量：258.32
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

SORT-PGRN interaction inhibitor 1 is a potent inhibitor of the sortilin-progranulin interaction with an IC50 of 2 μM[1].

SORT-PGRN interaction inhibitor 1 (Compound 2) with sufficient potency and physicochemical properties to enable co-crystallization with sortilin[1].

[1]. Shawn J Stachel, et al. Identification of potent inhibitors of the sortilin-progranulin interaction. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127403.