您好,欢迎来到试剂信息网! [登录] [免费注册]
试剂信息网
位置:首页 > 产品库 > OB 24 hydrochloride
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
OB 24 hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
OB 24 hydrochloride图片
规格:98%
分子量:373.67
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
Potent and selective heme oxygenase 1 (HO-1) inhibitor
货号:ajcx27392
CAS:939825-12-4
分子式:C15H17BrN2O2.HCl
分子量:373.67
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Potent and selective heme oxygenase 1 (HO-1) inhibitor (IC50 values are 1.9 and >100 μM for HO-1 and HO-2 respectively), reduces protein carbonylation and reactive oxygen species formation in advanced prostate cancer cells (PCA). Inhibits cell proliferation in vitro and PCA tumor growth and lymph node/lung metastases in vivo. Synergizes with Taxol .


Alaoui-Jamali et al (2009) A novel experimental heme oxygenase-1-targeted therapy for hormone-refractory prostate cancer. Cancer Res. 69 8017 PMID:19808972