An internal standard for the quantification of rimonabant
货号:ajcx23434
CAS:929221-88-5
分子式:C22H11Cl3D10N4O
分子量：473.8
溶解度:Chloroform: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Rimonabant-d₁₀contains 10 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, and 6' positions. It is intended for use as an internal standard for the quantification of rimonabant by GC- or LC-MS. Rimonabant, also known as SR141716, was the first selective central cannabinoid (CB₁) receptor inverse agonist (K_i= 1.8 nM) to be developed as an appetite suppressant and anti-obesity drug.¹It is widely used as a tool to investigate CB receptor properties and the mechanisms by which CB agonists exert their pharmacological effects.

1.Rinaldi-Carmona, M., Barth, F., HÉaulme, M., et al.SR141716A, a potent and selective antagonist of the brain cannabinoid receptorFEBS Letters350(2-3)240-244(1994)