A PKC inhibitor
货号:ajcx22758
CAS:105114-22-5
分子式:C26H23N3O5
分子量：457.5
溶解度:DMSO: soluble,Ethanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

K252d is an indolocarbazole alkaloid found inNocardiopsis.¹It is a PKC inhibitor that inhibits PKC isolated from rat brain (IC₅₀= 350 nM). It also inhibits calcium- and calmodulin-dependent phosphodiesterase isolated from bovine heart (IC₅₀= 46.2 µM).

1.Nakanishi, S., Matsuda, Y., Iwahashi, K., et al.K-252b, c and d, potent inhibitors of protein kinase C from microbial originJ. Antibiot. (Tokyo) 39(8)1066-1071(1986)