PROTAC IRAK4 degrader-1 是一种 PROTAC IRAK4 降解剂，详细信息请参考专利文献 US20190192668A1 中的化合物 I-210。PROTAC IRAK4 degrader-1 浓度为 0.01，0.1 和 1 μM 时作用于 OCI-LY-10 细胞，分别造成 20-50% 和 >50% IRAK4 蛋白降解。
货号:ajcx33246
CAS:2360533-90-8
分子式:C44H39F3N12O7
分子量：904.85
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.