Orexinreceptorantagonist2是一种有效的增食欲素受体(orexinreceptor)拮抗剂,pKi分别为7.69和9.78。Orexinreceptorantagonist2在失眠症研究中具有潜力。
货号:ajcx32420
CAS:1457940-75-8
分子式:C25H31N5O2
分子量:433.55
溶解度:DMSO: 62.5 mg/mL (144.16 mM; ultrasonic and warming and heat to 60°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78. Orexin receptor antagonist 2 has the potential for the research of insomnia[1].
[1]. Betschart C, et al. Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia. J Med Chem. 2013;56(19):7590-7607.