4-Hydroxymethylpyrazole 是 Fomepizole 的初级代谢产物。Fomepizole 是一种竞争的乙醇脱氢酶抑制剂。
货号:ajcx17116
CAS:25222-43-9
分子式:C4H6N2O
分子量:98.1
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:
现货Background:
4-Hydroxymethylpyrazole is the primary metabolite of Fomepizole . Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase[1].
[1]. R Blomstrand, et al. Pyrazoles as Inhibitors of Alcohol Oxidation and as Important Tools in Alcohol Research: An Approach to Therapy Against Methanol Poisoning. Proc Natl Acad Sci U S A . 1979 Jul;76(7):3499-503.