BCN-PEG3-Biotin 是一种不可降解 (non-cleavable) 的含 3 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
货号:ajcx36256
CAS:N/A
分子式:C29H46N4O7S
分子量:594.76
溶解度:DMSO : 100 mg/mL (168.14 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.