L 741742 (free base) is a potent and highly selective D4 dopamine receptor antagonist, with Kis of > 1700, 770 and 3.5 nM at cloned human D2, D3 and D4 receptors. References: Root DH, Hoffman AF, Good CH, Zhang S, Gigante E, Lupica CR, Morales M. Norepinephrine activates dopamine D4 receptors in the rat lateral habenula. J Neurosci. 2015 Feb 25;35(8):3460-9. doi: 10.1523/JNEUROSCI.4525-13.2015. PubMed PMID: 25716845; PubMed Central PMCID: PMC4339355.
纯度:≥98%
CAS:156337-32-5