C19H26ClN7O3.XCF3COOH
货号:ajcx19340
CAS:N/A
分子式:C19H26ClN7O3.XCF3COOH
分子量：435.9
溶解度:Methyl Acetate: Soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CAY10729 is a tetrazole derivative of the protein arginine deiminase (PAD) inhibitor Cl-amidine that selectively inhibits PAD1 over PAD2, PAD3, and PAD4 (kinact/KI = 162,200, 60,000, 17,500, and 25,400 M-1min-1 for PAD1-4, respectively).1

参考文献
1. Subramanian, V., Knight, J.S., Parelkar, S., et al. Design, synthesis, and biological evaluation of tetrazole analogs of cl-amidine as protein arginine deiminase inhibitors. Journal of Medicinal Chemistry 58(3), 1337-1344 (2015).