LHVS 是有效的，非选择性的 cysteine protease 抑制剂，LHVS 有效阻断 T. gondii 微素蛋白分泌 (IC50=10 μM)，滑动运动和细胞侵袭。
货号:ajcx15402
CAS:170111-28-1
分子式:C28H37N3O5S
分子量：527.68
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

LHVS is a potent, non-selective cysteine protease inhibitor[1]. LHVS effectively blocks T. gondii microneme protein secretion (IC50=10 μM), gliding motility, and cell invasion[2].

[1]. Wilson SR, et al. Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption. J Biol Chem. 2009 Jan 23;284(4):2584-92. [2]. Teo CF, et al.Cysteine protease inhibitors block Toxoplasma gondii microneme secretion and cell invasion. Antimicrob Agents Chemother. 2007 Feb;51(2):679-88.