DBCO-PEG4-Maleimide是一种可降解(cleavable)的ADClinker,用于抗体偶联药物(ADCs)的合成。
货号:ajcx31854
CAS:1480516-75-3
分子式:C36H42N4O9
分子量:674.74
溶解度:DMSO: 50 mg/mL (74.10 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
[1]. Xiaotian Zhong, et al. Capped and uncapped antibody cysteines, and their use in antibody-drug conjugation. WO2017025897A2.