α-Conotoxin PnIA TFA 是一种有效的选择性哺乳动物 α7nAChR 拮抗剂,具有研究神经性疼痛和阿尔茨海默氏病等神经系统疾病的潜力。
货号:ajcx36236
CAS:N/A
分子式:C67H96F3N19O24S4
分子量:1736.82
溶解度:DMSO : 100 mg/mL (57.58 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
α-Conotoxin PnIA TFA, a potent and selective antagonist of the mammalian α7 nAChR, has the potential for the research of neurological conditions such as neuropathic pain and Alzheimer’s disease[1].
[1]. Gene Hopping, et al. Hydrophobic Residues at Position 10 of α-conotoxin PnIA Influence Subtype Selectivity Between α7 and α3β2 Neuronal Nicotinic Acetylcholine Receptors. Biochem Pharmacol. 2014 Oct 15;91(4):534-42.