DBCO-PEG4-Biotin是一种含生物素基团和4个PEG的azadibenzocyclooctyne-biotin衍生物。DBCO-PEG4-Biotin是一种用途广泛的生物素酰化试剂，能通过无铜催化烷基叠氮化反应(SPAAC)将生物素的一部分引入叠氮标记的生物分子中。
货号:ajcx32032
CAS:1255942-07-4
分子式:C39H51N5O8S
分子量：749.92
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative containing a biotin group and 4 PEGs. DBCO-PEG4-Biotin is a versatile biotinylation reagent used for the introduction of a biotin moiety to azide-labeled biomolecules via copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reaction[1].

The alkyne group can react with azide moiety in copper-free Click Chemistry reaction to form a stable triazole linkage.

[1]. Hammink R, et al. Affinity-Based Purification of Polyisocyanopeptide Bioconjugates. Bioconjug Chem. 2017 Oct 18;28(10):2560-2568.