RebamipideD4(OPC12759D4)是Rebamipide的氘代物。Rebamipide是一种粘膜保护剂。Rebamipide诱导COX-2表达,增加PGE2水平,且以COX-2依赖性方式增强胃粘膜防御。
货号:ajcx31384
CAS:1219409-06-9
分子式:C19H11D4ClN2O4
分子量:374.81
溶解度:DMSO: soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Rebamipide D4 (OPC12759 D4) is deuterium labeled Rebamipide. Rebamipide is a mucoprotective agent. Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner[1].
[1]. Sun WH, et al. Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent. J Pharmacol Exp Ther. 2000 Nov;295(2):447-52.