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Mal-PEG2-oxyamine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mal-PEG2-oxyamine图片
包装:100mg
规格:98%
市场价:6615元
分子量:244.24

产品介绍
Mal-PEG2-oxyamine是一种PROTAClinker,属于PEG类。可用于合成PROTAC分子。
货号:ajcx30990
CAS:1146245-73-9
分子式:C10H16N2O5
分子量:244.24
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Mal-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.