LMD-009是选择性CCR8非肽激动剂。LMD-009以高效力介导趋化性，肌醇磷酸盐积累和钙释放，EC50为11至87nM。
货号:ajcx30934
CAS:950195-51-4
分子式:C29H33N3O3
分子量：471.59
溶解度:DMSO: 250 mg/mL (530.12 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

LMD-009 is a selective CCR8 nonpeptide agonist. LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM[1].

[1]. Jensen PC, et al. Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8. Mol Pharmacol. 2007 Aug;72(2):327-40.