Fmoc-Gly3-Val-Cit-PAB是一种可降解(cleavable)的ADClinker，可用于合成抗体偶联药物(ADC)。
货号:ajcx30668
CAS:N/A
分子式:C39H48N8O9
分子量：772.85
溶解度:DMSO: 100 mg/mL (129.39 mM); H2O:< 0.1 mg/mL (insoluble)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Fmoc-Gly3-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.